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1.
J Contemp Dent Pract ; 25(2): 114-117, 2024 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-38514407

RESUMO

AIM: The study aims is to evaluate the antibacterial effect of vitamin D3 against the red complex bacteria, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia in chronic periodontitis patients. MATERIALS AND METHODS: The study comprised 98 participants with chronic periodontitis. All clinical parameters including plaque index (PI), gingival bleeding index (GBI), probing pocket depth (PPD), clinical attachment level (CAL), and a microbiological assay of P. gingivalis, T. denticola, T. forsythia were assessed at the baseline. All study participants who underwent scaling and root planning were divided into two groups, A and B, each with 49 patients and only group B patients were advised to take vitamin D supplementation of 60,000 IU granules, once daily for 2 months. All the patients of both the groups were recalled at the end of 2nd month and all the clinical and microbiological parameters were reassessed. RESULTS: After two months, there was a reduction in all the clinical markers in both groups, but the group B patients showed more improvement following non-surgical treatment vitamin D intake. There was also a statistical reduction in P. gingivalis, T. denticola, and T. forsythia following administration of vitamin D in group B patients compared to group A. CONCLUSION: These discoveries proposed that vitamin D has a superb antimicrobial impact against red complex periodontal microbes and might be considered a promising compound in the counteraction of periodontal disease. CLINICAL SIGNIFICANCE: Vitamin D is considered to possess anti-inflammatory and antimicrobial activity, which may help to delay the progression of periodontitis. So, vitamin D3 can be used as a potential supplement that could be employed to stop the advancement of periodontal disease. How to cite this article: Govindharajulu R, Syed NK, Sukumaran B, et al. Assessment of the Antibacterial Effect of Vitamin D3 against Red Complex Periodontal Pathogens: A Microbiological Assay. J Contemp Dent Pract 2024;25(2):114-117.


Assuntos
Periodontite Crônica , Humanos , Periodontite Crônica/tratamento farmacológico , Periodontite Crônica/microbiologia , Colecalciferol/farmacologia , Colecalciferol/uso terapêutico , Bolsa Periodontal , Porphyromonas gingivalis , Antibacterianos/farmacologia , Antibacterianos/uso terapêutico , Perda da Inserção Periodontal/terapia , Aggregatibacter actinomycetemcomitans
2.
J Pharm Bioallied Sci ; 13(Suppl 1): S778-S782, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34447200

RESUMO

BACKGROUND AND OBJECTIVES: The maxillary central incisor is the dominant element of anterior dental composition and hence should be restored or replaced with proper proportion of width and length for better aesthetic results. However, the literature is not clear regarding verifiable guidelines for the determination of proportions of the teeth. The aim of this study was to investigate the existence and suitability of Golden Rectangle, Recurring Aesthetic Dental Proportion, and Golden percentage between the widths of maxillary anterior teeth in individuals with natural dentition, with the aid of digital photographs and computer analysis. MATERIAL AND METHODS: Frontal full-face digital photographs of the subjects (in smile) were made under standardized conditions using a digital camera and a tripod stand was used to place and orient the camera in the standardized position (camera was positioned 1 meter away from the patient; and the lens of the camera was adjusted at the patients' lip level). Imaging software (Adobe Photoshop CS5; Adobe Systems, Inc, San Jose, Calif.) was used to mark the anatomic landmarks and to digitally analyze the photograph. The entire process of proportion analysis was done by a single observer. RESULTS: The RED proportion was not found to exist between the six maxillary anterior teeth. The values suggested in the golden percentage were not applicable on the subjects of this study. However, a slight modification of these percentages can be adopted taking into consideration the ethnicity differences of the subjects in this study. The values obtained were 24%, 15%, 11% in males and 23%, 15%, and 11% in females. Golden rectangle concept can be used for choosing dimensions of maxillary central incisors which are esthetically pleasing. CONCLUSION: RED proportion is an unsuitable methods to relate the successive widths of the maxillary anterior teeth. The golden percentage theory seems to be applicable to relate the successive widths of the maxillary anterior teeth if percentages are adjusted taking into consideration the ethnicity of the population. Golden rectangle concept is suitable for choosing dimensions of maxillary central incisors which are esthetically pleasing.

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